While this feature is available on many third-party apps, it’s not on the browser. However, since you’re already using an ad blocker, you can use it to filter out content as well.
To filter out posts with certain keywords, go to your custom filters and add this code. For example, to hide all posts containing the word “Elon”:
lemmy.world##div.post-listing:has(span:has-text("/elon/i"))
If your instance is something other than lemmy.world, just replace it with the correct domain.
To filter out comments, use this:
lemmy.world##article.comment-node:has(div.comment-content:has(p:has-text(/asshole/i)))
To add more keywords, simply duplicate the code and replace the keyword with another.
I have a low level hardware filter for that on my brain’s innate ignore list.