It’s a bit ambiguous, so you could be right, but I took it to mean that activation of the receptors was that active mechanism, regardless of cause. Psilicin is just the compound they’re focused on, and maybe it does activate them in some unique way that has this effect, but the summary didn’t make that clear.
If there are alternative pathways to activate the receptors they may be better suited to thereputic use without the psycadelic side effects.
I haven’t gone looking forthe souce paper, but from the article it looks like seretonin was the actual compound that’s having a beneficial effect, specifically serotonin outside the brain.
While there’s probably no global solution, personally I use a QR Code reader that doesn’t actually use the URL, but just displays it and lets me copy it to the clipboard. That way I can inspect it, and if it doesn’t look right, ignore it.
This is excellent article on enshitification, some of the factors that can lead to it, and ways founders could think about it to hopefully avoid it. What it doesn’t seem to talk about is how Tailscale intends to avoid it, now and in the future.
The joys of distributed algorithms. You can now get more errors, more quickly than before!
I remember writing a chat system in assembler, for DOS, using, IIRC, IPX networking. When it went wrong, one or more machines would just freeze, with the string “NETWORK ABEND” in the middle of the screen.
I should fork vim and call it ‘death’, so I can shout “give me vim or give me death!” any time someone suggests a different editor.
That has unironicaly made me nostalgic for the days when the web was a place of experimentation, joy and just a bit of crazy.
Once you realise that most people don’t read most of the information you give them, it sort of becomes a secret power. You can hide all sorts of things in a five paragraph email, let alone a full report.
I started offering cash prizes in the middle of reports, to be claimed simply by telling me you’d read that bit. Not a single taker. I stopped writing the reports after that, and no one noticed.
“…ok”
I’d love to think that his next words involved acknowledging that he didn’t know what he’s talking about, but they didn’t, did they?