Who reads this anyway? Nobody, that’s who. I could write just about anything here, and it wouldn’t make a difference. As a matter of fact, I’m kinda curious to find out how much text can you dump in here. If you’re like really verbose, you could go on and on about any pointless…[no more than this]

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Cake day: June 5th, 2023

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  • Doing chemistry by mixing chemicals is like fumbling in the dark. You tend to have ridiculously low yield, because you can’t really control which reaction takes place. It’s just a game of probabilities, which makes this gamble really expensive.

    Living cells are doing chemistry the right way by combining specific materials and making specific products. Enzymes are very picky, but with them you can actually control the reactions. Making enzymes is just next level complexity and a story for another time.




  • As someone who is severely allergic to ads, I really don’t like this transition, but I understand why they’re doing it.

    Mozilla seems to be facing a tough problem. How do you make money when your core audience isn’t enough to support the company, but you can’t realistically pivot to a new audience without kicking out all of the old users. Would it be better if Mozilla just faded into irrelevancy and focussed on developing Thunderbird instead? The FOSS community would have to continue to support Firefox, which would slow down development to such an extent that it probably wouldn’t be able to keep up with the rest of the web.




  • Not that many people use real computers any more. At work, you may need to use a computer, but you probably can’t change the browser. At home, you have the PCMR folks who use a computer and probably also care about browsers. Everyone else just uses a tablet or a phone for browsing the web.

    Speaking of the web, most people interact with specific websites through an app and an API, so they don’t even launch the mobile browser until they have to visit a site that doesn’t have an app. The world has changed and browsers aren’t as relevant as they used to be.













  • The idea of modern medicine is to sell chemical compounds that actually have an effect. It’s a philosophical and ethical thing. All products have a unique psychological effect that gets intertwined with their biochemical effect. If you can’t study them individually, it’s impossible to tell if the biochemical effect even exists at all. If your medicine relies heavily, or even entirely, on the psychological side, it’s no different than homeopathy. The idea of modern medicine is to be better than the old stuff that preceded it.

    I prefer to think of this as an equation like this: Pm+Bm=Pp+Bp

    Pm=psychological effect, medicine

    Bm=biochemical effect, medicine

    Pp=psychological effect, placebo = surprisingly big

    Bp=biochemical effect, placebo = 0

    If these sides are equivalent, the medicine is just as effective as placebo. If the medicine side is bigger, you’ll want to know how much of it comes from the P and B terms. In order to figure that out, you would need to know some values. Normally, you can just assume that Pm=Pp, but if you can’t assume that, it you’re left with two unknowns in that equation. In this case, you really can’t assume them to be equal, which means that your data won’t allow you to figure out how much of the total effect comes from psychological and biochemical effects. It could be 50/50, 10/90, who knows. That sort of uncertainty is a serious problem, because of the philosophical and ethical side of developing medicine.