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Joined 1 year ago
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Cake day: June 8th, 2023

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  • So this is neat. Potentially life changing for some type 2 diabetics, but that depends because some t2 diabetics are not failing to make enough insulin, they’re just no longer sensitive to it at a level that makes it functional for them. I suppose it’s possible that this therapy could cause them to grow enough islet β cells to overcome their lack of sensitivity, but (and I’m a type 1, not a type 2, so maybe my info is incorrect here) that lack of sensitivity can grow with further exposure to insulin making this a stop-gap at best for those cases absent other therapies.

    …and with all of that said, being able to regrow islet β cells has never really been the problem for type 1 diabetes. You can regrow all the islet β cells you’d like and it’s not going to cure the underlying immune disease that has caused your immune system to kill off all of your islet β cells to begin with. Unless you can figure out why t1 diabetes causes one’s own immune system to go psycho killer on their islet β cells, you’ve done nothing to “cure” diabetes. Without being able to suppress that impulse for your immune system to murder your own cells, any ability to replace the islet β cells is going to be temporary at best, and probably a waste on the whole.

    My brother in law is a “cured” type 1 diabetic, by virtue of his having had a kidney replacement and being on immune suppressing drugs for that. Since they were already replacing the kidney and he was going to have to take immune system suppression medications for that, they also just replaced his pancreas at the same time and the suppression of his immune system has allowed the new pancreas to thrive and continue to make insulin. Easy-peasy. The only trade-off is that he is super immunocompromised and can be killed by common colds, so not a great strategy in general.



  • At this point they’re only wagging their fingers to make it appear as though they’re considering regulation.

    Again, it’s disingenuous to claim that their pragmatism in the face of unreasonable actors is the same as being the unreasonable actors. What are the left supposed to do? Pull a Trump and pretend that the laws and systems that make our country don’t exist and just say that what they want is law and ignore that half the country is electing morons who will fight them at every turn? That’s not how it works and frankly I wouldn’t want it to work that way because it’s just incredibly dangerous. They’re trying to work within a system where the right has learned they can con half the country into believing they’re doing their job while they sit back and do their damnedest to ensure that the government doesn’t function at all because that’s the only way that conservatives can stop progress at this point with their platforms being as unpopular as they are.


  • The left is definitely more open to considering regulation. It’s not even close. The right thinks that regulation is a four letter word and they’re generally not a fan of those either. It’s disingenuous to both sides everything. Much of the time where the left allows a carveout for vampirism, it’s because it’s the best compromise they can mange to a given end given that the right is out there swabbing their throats and getting all hot and bothered waiting for daddy Drac to come and give it to them, not because it’s their preference that we allow unfettered late-stage capitalism to destroy lives. Again, it’s disingenuous to claim that their pragmatism in the face of unreasonable actors is the same as being the unreasonable actors (and I am well aware that there are exceptions that prove the rule on both sides of the isle, so 🤷‍♂️)

    …and lest anyone think that this problem isn’t solved with government regulation, I invite you to look at the medication situation in nearly any other country in the world where by and large they are not afraid of regulation for the same drug companies that are fucking us sideways in the US and see how much cheaper and better their access to medications is solely because they’re willing to support that maybe there is a greater public good than shareholder profits.









  • Your Mastodon data is already an open book to Meta if they care to have it. The protocol is open, they could already be black-ops scooping up everything that’s fit to federate without turning on Threads federation, so them doing that really changes nothing. And what I mean by that is that they could already have set up unknown instances to leech whatever data they want out of the Fediverse, which instances masquerade as normal mom and pop installs just federating and sucking up everything without bringing anything back to the table. There’s literally nothing stopping them from leeching everything out of the Fediverse at any time other than people being better at detecting their activity (and actively thwarting that activity) than Meta is at keeping it off the radar.

    In this case they’re making it so that I might have a chance to follow and interact with people already in the Meta/Instagram/Threads atmosphere without having to convince those people to leave the confines of what they’re comfortable with and find a Mastodon instance to sign up for. Maybe they’ll be more comfortable with leaving Meta after dipping their toes in the open spec?

    How is that not a win? If Meta/Threads decide that they want to fracture the protocol and go do their own thing later, so what? We’ll go right back to where we were before they brought their users into the Fediverse. If people decide that they value the Threads extras/connections more than they value the purity of the ActivityPub protocol then maybe Meta is actually providing something that matters and we’ve lost by not supplying that need before the corporate interest figured out that it existed. In that case we’ll deserve the death that causes in use of the open spec, but the open spec will still be there and people who want to do their own thing with it can’t be stopped now. The code to run an open ActivityPub Mastodon instance is already out there and it’s impossible to take it back now.

    Everyone is out here decrying this as a subtle takeover of the Fediverse by Meta, but did Facebook “takeover” the HTTP spec when they started operating facebook (dot) com on the world wide web over the HTTP protocol? It’s an insane assertion. I’ve been running my own opensource web servers since well before Facebook was a thing and I’ve continued to do so despite most people opting to depend on a mega-corp to be steward of their online presence. That Meta has a very successful and popular website that I’ve never been a fan of has never impacted my ability to use the open protocol they operate on to continue doing my own thing. The same thing will be true here.

    It really seems like people are just upset that Threads might bring ActivityPub to the mainstream and force them to contend with the realization that a diaspora of open spec implementations already lost the war to Meta/Facebook. We had that once before. It was called the World Wide Web and you could go and find forums, fan pages, company websites, and everything else back then that has since moved to Facebook (or other content aggregator sites) because people value the network effects and homogenization more than they care about one big company being in charge of it all. (…and not to belabor the point, but most of that stuff is still out there, it’s just waned in popularity because the network effects are not there.) Here we are with a chance to try and break things out again and people are seemingly worried that we can’t if we let the Meta users in? Maybe they’re right, maybe it’s impossible to achieve victory here, but gatekeeping the standard and enacting some purity test for which providers are allowed on the protocol isn’t going to tip the scales in favor of the open standards implementation.

    If the protocol is truly open, then how can a corporation embracing it be a danger? We’re all free to adopt any changes or not at any point in the journey so it’s impossible to lose, you’re free to keep doing your own thing any way you look at it. Tell me how any of this is untrue.

    TL;DR: Threads coming to the Fediverse is a good thing. It’ll make it possible to expand the network effects of an open protocol far faster and more than any amount of Fedinerds proselyting the gospel of ActivityPub ever will. The only thing that is at risk of being lost is that we’ll refuse to adapt to what end users want fast enough to keep a large corporation from bending the spec to their ends. Which loss again only means that you’d be cutting yourself off from those who WANT to embrace the revised spec by not adopting those changes yourself. That option (to just not adopt changes to the spec) can’t be taken away from you in the future, so worrying is only warranted if you feel like your ideal ActivityPub implementation can’t win out in the marketplace of ideas and that you’re owed that victory even if others are able to expand it in ways that people actually want to use enough to dismiss whatever downsides it contains.


  • I’ve a Mazda with Android Auto that doesn’t use a touch screen. It’s all controlled with a joystick/knob/button setup that is actually really nice. I wish my Nissan had a similar setup all the time.

    In the Mazda I know how many physical interactions will get me the result I want, it takes barely more than a glance at the screen to know what’s up. With the touch interface I have to put my eyes on the screen to confirm that the car didn’t bounce when I went to tap a “button” and/or confirm that the tap was actually registered. I know that GM has to know that Android Auto supports non touchscreen interactions. If they’re concerned about how unsafe touchscreens are, just add a knob to the center console that doubles as a 4-way joystick like Mazda has and all those concerns go away. It’s really that simple and it IS miles better than using touch for everything.




  • Any sites that attempted to restrict browser access based on WEI signals alone would have also restricted access to a significant enough proportion of attestable devices to disincentivize this behavior.

    If it’s actually a “significant enough proportion of attestable devices to disincentivize this behavior” why would anyone want to rely on this mechanism? I have a means to check if a device should be trusted, but it fails enough of the time that I shouldn’t depend on it… Why would I ever depend on it? What use case allows for an expected 10% failure rate?


  • The objective of WEI is to provide a signal that a device can be trusted

    This is exactly the opposite of everything anyone would learn in CompSci 101.

    NEVER TRUST THE CLIENT. CLIENTS CANNOT BE TRUSTED. CLIENTS ARE NOT SANE. THAR BE DRAGONS THERE. (Maybe that last one is pirate treasure maps, but I think it holds.)

    Anyone who is buying this guy’s argument that they’re trying to make it so you can trust clients, should immediately be removed from any computers they are in possession of and be “invited” by men in black suits to go live on a nice agrarian farm where the only computer available is an air-gapped Tandy TRS-80 MC-10. They can rejoin humanity when they’ve relearned the lessons of the last 40 years and understand why this is just patently insane.