Their jokes about assigning gender to babies and to being transgender, dressing in drag, like all of it was a send-up.
Sure, they did punch down if you were a person who were in those groups, but the fact that it was large enough social event to be relevant enough to be a comedy skit on a television show or a movie seen by millions implies that there were some serious things going on back then that they could see and wanted to address.
What the hell was going on that put all of those things in their mind?
I once read a novel from the 1970s. There were a couple of thugs who were arguing over who’d had more STIs. It was a simpler, happier time.
Never had one. If you get tested prior to each new partner, and require the same from them, it’s remarkably easy to avoid, as long as you don’t participate in hook-up culture.